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Soma (carisoprodol) is a centrally acting skeletal muscle relaxant approved by the FDA for short-term relief of acute musculoskeletal pain. It works by inhibiting pain signals between the nerves and the brain. Typically prescribed for conditions like muscle spasms, strains, and sprains, Soma is intended for short-term use, usually not exceeding two to three weeks, to minimize risks of dependence and abuse.

Pharmacological Profile:
Carisoprodol is metabolized in the liver to meprobamate, a substance with anxiolytic and sedative properties. This metabolite contributes to the therapeutic effects but also to the potential for abuse and dependence.

Efficacy and Safety:
Clinical studies have demonstrated that carisoprodol is effective in reducing pain and improving mobility in patients with acute lower back pain. A randomized, double-blind trial found that both 250 mg and 350 mg doses administered four times daily provided significant relief compared to placebo.

Side Effects and Risks:
Common side effects include drowsiness, dizziness, and headache. Serious adverse reactions may involve seizures, hypotension, and respiratory depression, especially in cases of overdose. Prolonged use can lead to dependence and withdrawal symptoms.

Contraindications:
Soma should not be used in patients with a history of drug abuse, those concurrently using other CNS depressants, or individuals with certain medical conditions.